CRYOABLATION OF THE PROSTATE AND KIDNEY
Prostate cryosurgery
- Minimally invasive
- Outpatient procedure
- Can be performed with a spinal block
- Appropriate for low, moderate and high-risk patients
- Treatment option for post-radiation recurrence patients
- Technology improvements provide precise treatment

CRYOCARE CS® system
- Integrated ultrasound imaging
- CRYOGUIDE™ planning software
- Individual probe control
- TEMPPROBE™ temperature monitoring system
- Closed-loop urethral warming system
V-PROBE® cryoprobe
5 Position variable cryoprobe instrument
- Next generation technology allows physicians to adjust the length of the isotherm to fit the prostate
- Works with Endocare’s intraoperative prostate planning software to calculate cryoprobe placement and iceball length
- Variable slider creates 5 different isotherms from the same cryoprobe; 1.5cm to 5.0cm

Primary & salvage examples
Ability to safely treat primary & salvage due to the variability of the ice
This illustration demonstrates the use of six V-PROBE cryoprobes positioned on both sides of the prostate separated by <2.0 cm. The V-PROBE isotherms are adjusted based on the size of the prostate so that only the prostate is encapsulated in lethal ice (<-40 ̊C). In this illustration, the ice balls from the V-PROBE cryoprobes are still forming and will eventually coalesce (typically at 10 minutes).

Ability to treat capsular extension
If a small amount of extra-capsular extension is a concern, V-PROBES may also be placed at the lateral edges of the gland so that the ice extends beyond the lateral capsule of the prostate as shown in this illustration.

Renal cryosurgery
- Nephron sparing treatment
- Ability to treat tumors involving the collecting system
- Minimally invasive method of treating incidental tumors
Right angle SLIMLINE™ renal probes
- Multiple ice ball sizes, probe lengths, and diameters.

Cryoprobe technology
- Patented Vacuum Insulation minimizes freezing up the shaft and patient skin damage.

Renal tumor freeze using one 3.8mm cryoprobe
This illustration demonstrates the use of one 3.8mm right angle cryoprobe positioned at the center of the tumor. The freeze encapsulates the entire tumor with lethal ice (<-40°C). In this illustration, the ice ball from the cryoprobe is still forming and will eventually reach its maximum size (typically at ten minutes). An extra ablation margin is created by extending the ice a minimum of 1cm beyond the tumor.
Renal tumor freeze using two 2.4mm cryoprobes
This illustration demonstrates the use of two 2.4mm right angle cryoprobes positioned on both sides of the tumor and separated by <2.0cm. The freeze encapsulates the entire tumor with lethal ice (<-40oC). In this illustration, the ice balls from the cryoprobes are still forming and will eventually coalesce (typically at ten minutes). An extra ablation margin is created by extending the ice a minimum of 1cm beyond the tumor.
Renal tumor freeze using three 1.7mm cryoprobes
This illustration demonstrates the use of three 1.7mm right angle cryoprobes positioned on both sides and center to the tumor and separated by <1.0cm. A freeze encapsulates the entire tumor with lethal ice (<-40oC). In this illustration, the ice balls from the cryoprobes are still forming and will eventually coalesce (typically at ten minutes). An extra ablation margin is created by extending the ice a minimum of 1cm beyond the tumor.
Important Safety Notice: Varian products used to treat cancer and other conditions pose the risk of side effects, which can vary based on the treatment modality and part of the body being treated. Safety information regarding risks associated with the use of our products can be found on our Safety Information page.